Liuqiao area in south China is an ideal place for high-resolution definition of the deep-water Permian-Triassic boundary (PTB) and correlating deep-water and shallow marine PTB sequences. It contains contemporaneous deep-water basin and shallow marine platform facies deposited in a latest Permian archipelagic palaeogeographic setting. Multidisciplinary stratigraphic data were analyzed for the first time from a well-preserved deep-water PTB section (Dongpan section) and used to define and correlate the PTB in the Liuqiao area. By applying the PTB Stratigraphic set (PTBST) concept, some important stratigraphic characteristics across the PTB were discovered including: (1) different clay mineral compositions across the PTBST; (2) radiolarian biodiversity decreased abruptly and showed step-by-step extinction across the PTBST; and (3) the most negative excursion of ?13 Corg values occurred in the PTBST. The global correlation was also compared by multidisciplinary stratigraphy between the Dongpan section and GSSP in the Meishan section. The correlation was based on the lithostratigraphical, event-stratigraphic (the boundary clay beds), biostratigraphic (radiolarian fossil assemblages), and chemostratigraphic (organic carbon isotope excursion signals) evidence. We conclude that a well-defined PTB succession is recognizable in the deep-water section of Dongpan.